Interest in the abnormal metabolism displayed by cancer cells has been reawakened by the discovery of oncogenic mutations in metabolic enzymes, and also by devices that screen metabolism in life cells. Existing and also emerging therapies aim to target this abnormal line in various ways.

You are watching: When oxygen is plentiful, pyruvate from glucose is converted to


All prices space NET prices. VAT will certainly be added later in the checkout.Tax calculation will be finalised throughout checkout.

See more: How Do You Say Thankful In Spanish (Plus Phrases For You'Re Welcome)


*

*

Affiliations

William G. Kaelin Jr is in ~ the Howard Hughes clinical Institute, and also at the Dana-Farber Cancer Institute and also Brigham and Women"s Hospital, Harvard clinical School, Boston, Massachusetts 02115, USA. William_kaelin
dfci.harvard.edu;

William G. Kaelin Jr

Craig B. Thompson is at the Abramson Cancer Center and Abramson household Cancer study Institute, college of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. Craig

Competing interests

W.G.K. Is a consultant to FibroGen Pharmaceuticals and to Agios Pharmaceuticals. C.B.T. Is a founder and chair the the advisory board of Agios Pharmaceuticals.


Cite this article

Kaelin, W., Thompson, C. Hints from cabinet metabolism. benidormclubdeportivo.org 465, 562–564 (2010). Https://doi.org/10.1038/465562a

Download citation

Published: 02 June 2010

Issue Date: 03 June 2010


Share this article

Anyone girlfriend share the following connect with will have the ability to read this content:

Get shareable link

AMPK activation overcomes anti-EGFR antibody resistance induced through KRAS mutation in colorectal cancer

Hua Ye, Yi Liu, Kefeng Wu, Hui Luo&Liao Cui

cabinet Communication and also Signaling (2020)

A multicentre clinical validation of AminoIndex Cancer Screening (AICS)

Haruo Mikami, Osamu Kimura, Hiroshi Yamamoto, Shinya Kikuchi, Yohko Nakamura, Toshihiko Ando&Minoru Yamakado

clinical Reports (2019)

FELLA: an R package come enrich metabolomics data

Sergio Picart-Armada, Francesc Fernández-Albert, Maria Vinaixa, Oscar Yanes&Alexandre Perera-Lluna

BMC bioinformatics (2018)

Novel non-invasive early detection that lung cancer using liquid immunobiopsy metabolic task profiles

Yochai Adir, Shoval Tirman, Shirley Abramovitch, Cynthia Botbol, Aviv Lutaty, Tali Scheinmann, Eyal Davidovits, Irit Arbel, Giora Davidovits, Sonia Schneer, Michal Shteinberg, Hagit Peretz Soroka, Ruven Tirosh&Fernando Patolsky

Cancer Immunology, Immunotherapy (2018)

emerging roles of lipid management in cancer metastasis

Xiangjian Luo, have the right to Cheng, Zheqiong Tan, Namei Li, Min Tang, Lifang Yang&Ya Cao

molecular Cancer (2017)